The present study was conducted to investigate the Caprine and Ovine Theileriosis in district Zhob of Balochistan, two populated /union councils were included in the study area. Samples were collected from prescapular swollen lymph nodes 120 animals Sheep (n= 60) and Goats (n= 60) for screening of the disease. Blood collected from suspected animals and smears were prepared to identify the Theileria. After conformation, the positive cases send to Laboratory for hemato-biochemical analysis.
Data revealed 21.66% disease in sheep and 10% goats. Hemato-biochemical parameters were done before and after chemotherapy three times interval. Effect of theileriosis in sheep and goats were studied which included RBCs, Hb%, PCV, RDWC, HCT, MCV, MCHC, WBCs, , Platelets, Creatinine, Urea, Uric Acid, ALT, ALP and Bilirubin. Blood samples were collected from Theileria confirmed. In sheep RBCs, Hb%, PCV, RDWC, HCT, MCV, MCHC, WBCs, Platelets, Creatinine values showed significant difference when compared with normal values of healthy animals. Significant (p<0.05) reduction was noted in measurement of RBCs, Hb%, PCV and MCHC whereas, Urea, Uric Acid, Creatinine, ALT, ALP and Bilirubin showed significant (p<0.05) increase in diseased animals. In sheep and goats affected with theileriosis showed significant decrease in RBCs count and Hb%. The values for Urea, ALT, ALP, Uric acid, bilirubin and Creatinine were found significantly increased in diseased animals when compared with value of healthy animal whereas the association between age groups and theileriosis was studied. The animals were divided into three groups by age. The data showed a high difference of ratio of ages on disease. It was noticed that theileria increases with age of animals. In our investigation the highest number of positive animals was found in 4-4.5 years followed by 3.5-4 years and 3-3.5 years with percentage of 36.84%, 26.31% and 21.05%. In present study it was noted that Butalex intra muscularly at the rate of 2.5 mg/kg body weight along with oxytetracycline 1ml/10kg body weight is significant (p<0.05) to eliminating the Theileria parasite from the blood of sheep. Diminazene @ 4.2mg/kg body weight along with oxytetracycline @ 1ml/10kg body weight I/M were non-significant (p> 0.05) and less found an effective treatment for theileriosis and calotropis procera was effective for the treatment of theileria in goats @ 0.3mg/kg body weight orally up to five days daily.
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