The established cell lines; MDCK and Vero
were studied to find out transformation of
chromosome number. The various
techniques like G-Banding and C-banding
were also studied. The changes in
chromosome number were noticed which
could be related to number of passages given
to cell lines. Present studies observed 76
chromosomes minimum and 81 maximum in
MDCK cells, whereas 54 chromosomes
minimum and 61 maximum in case of Vero
cells. Hence the inconsistency in
chromosome number implies that the
MDCK cells have been moderately
transformed, which could be because of 15
and 21 passages respectively. 1343109787.php