Lameness is a multifactorial disease or abnormality that causes the cow to change the way it walks. Nutritional management continues to be a major focal point in the attempt to reduce lameness in dairy cattle. Scientific research is reporting significantly improved hoof health with dietary biotin supplementation. Biotin is a B-complex water-soluble vitamin that is essential nutrient for all animals. Biotin is possibly the vitamin of greatest importance to the keratinization process involved in pathways for amino acid metabolism, cellular respiration, gluconeogensis, and fatty acid synthesis. It is involved in the differentiation of epidermal that will become the hoof horn, in the production of keratin and intracellular cementing substance. Although biotin is present in many feedstuffs, scientists do not know how much of it is actually available to meet the cow’s needs. There have been few studies in any species on the bioavailability of the biotin found in feedstuffs. Increasing the bioavailability of biotin improves its utilization and thus contributes to an improved integrity of claw. Ruminants produce biotin as a result of bacterial fermentation, however ruminants receiving proportionately high-grain thus predisposing them to lactic acidosis which reduced the microbial synthesis of biotin tend to have more hoof problems especially during periparturient period and in early lactation. More recent studies have shown that in dairy cattle fed 10-20 mg per head supplemental biotin daily, hoof health was improved and the incidence of the common hoof problems was reduced. 1346913770.php